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1

Comparison of the Effects and Disposition Kinetics of Lidocaine and (±)Prilocaine in Patients Undergoing Axillary Brachial Plexus Block During Day Case Surgery

Marc A. M. Simon, Dr Tom B. Vree, Mathieu J. M. Gielen, Leo H. D. J. Booij, Aart J. Lagerwerf

Journal:

Clinical Drug Investigation

Year:

1998

Language:

english

File:

PDF, 294 KB

english, 1998

2

Regional metabolism of articaine in 10 patients undergoing intravenous regional anaesthesia during day case surgery

Tom B. Vree, Marc A. M. Simon, Mathieu J. M. Gielen, Leo H. D. J. Booij

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 365 KB

english, 1997

3

Pharmacokinetics, acetylation-deacetylation, renal clearance, and protein binding of sulphamerazine, N4-acetylsulphamerazine, and N4-trideuteroacetylsulphamerazine in ‘fast’ and ‘slow’ acetylators

Tom B. Vree, Chiel A. Hekster, Margriet Baakman, Tom Janssen, Marijn Oosterbaan, Emiel Termond, Marian Tijhuis

Journal:

Biopharmaceutics & Drug Disposition

Year:

1983

Language:

english

File:

PDF, 825 KB

english, 1983

4

The relationship between the renal clearance of creatinine and the apparent renal clearance of beta-2-microglobulin in patients with normal and impaired kidney function

Tom B. Vree, Pieter J.M. Guelen, Babs Jongman-Nix, Geert H.I.M. Walenkamp

Journal:

Clinica Chimica Acta

Year:

1981

Language:

english

File:

PDF, 387 KB

english, 1981

5

Multiple Absorption Patterns of Mesalazine from Two Gastroresistant Tablets in Healthy Male Volunteers

Dr Tom B. Vree, Erik Dammers, Peter S. Exler, Robert A. A. Maes

Journal:

Clinical Drug Investigation

Year:

2001

Language:

english

File:

PDF, 250 KB

english, 2001

6

Mono- and Biphasic Plasma Concentration-time Curves of Mesalazine from a 500 mg Suppository in Healthy Male Volunteers Controlled by the Time of Defecation before Dosing

TOM B. VREE, ERIK DAMMERS, PETER S. EXLER, ROBERT A. A. MAES

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

7

Pharmacokinetics and acetylation of sulfa-2-monomethoxine in humans

Tom B. Vree, Eleonora W. J. Beneken Kolmer, Yechiel A. Hekster, Minoru Shimoda, Makoto Ono, Tadayoshi Miura

Journal:

Biopharmaceutics & Drug Disposition

Year:

1992

Language:

english

File:

PDF, 604 KB

english, 1992

8

Neoadjuvant Bevacizumab, Oxaliplatin, 5-Fluorouracil, and Radiation for Rectal Cancer

Tom Dipetrillo, Victor Pricolo, Jorge Lagares-Garcia, Matt Vrees, Adam Klipfel, Tom Cataldo, William Sikov, Brendan McNulty, Joshua Shipley, Elliot Anderson, Humera Khurshid, Brigid Oconnor, Nicklas B

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 142 KB

english, 2012

9

Pharmacokinetics of 450 mg ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study

Schoenmakers, Karin P. W., Vree, Tom B., Jack, Nigel T. M., van den Bemt, Bart, van Limbeek, Jacques, Stienstra, Rudolf

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 701 KB

english, 2013

10

O-demethylation and N4-acetylation of sulfadimethoxine by the snail Cepaea hortensis.

VREE, Tom B., VREE, Monika L., BENEKEN KOLMER, Eleonora W. J., HEKSTER, Yechiel A., SHIMODA, Minoru, NOUWS, Jacques F. M., YOSHIOKA, Toshiyuki, HOJI, Kazuhiko

Journal:

The Japanese Journal of Veterinary Science

Year:

1989

File:

PDF, 616 KB

1989

11

Pharmacist-Physician Interaction: A Battle of Genes

Journal:

Year:

1991

Language:

english

File:

PDF, 180 KB

english, 1991

12

Pharmacokinetics and toxicology of sparsomycin in beagle dogs

Zbigniew Zylicz, D. J. Theo Wagener, Pilar Fernandez Moral, Helga Rennes, Johannes M. C. Wessels, Benjamin Winograd, Eppo Kleijn, Tom B. Vree, Urbanus Haelst, Leon A. G. M. Broek, Harry C. J. Ottenhei

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 939 KB

english, 1987

13

Acetylation of sulphamethoxazole by the snail Cepaea hortensis

TOM B. VREE, MON1 KA L. VREE

Journal:

Journal of Veterinary Pharmacology and Therapeutics

Year:

1984

Language:

english

File:

PDF, 177 KB

english, 1984

14

Male-Female Differences in the Plasma, Liver and Tissue Esterase Hydrolysis of Lovastatin in Healthy Volunteers after a Single Oral Dose

Dr Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Myroslav Ryska, Ijsbrand Merkx

Journal:

Clinical Drug Investigation

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

15

Upper and Lower Limits in the Renal Clearance of Acetylmesalazine in Humans

Dr Tom B. Vree, Erik Dammers, Peter S. Exler, Fritz Sörgel, Stig Bondesen, Robert A. A. Maes

Journal:

Clinical Drug Investigation

Year:

2001

Language:

english

File:

PDF, 225 KB

english, 2001

16

The in vitro effects of benzodiazepines on the rat diaphragm. Structure–activity relationships

Driessen, Jacques J., Egmond, Jan Van, Vree, Tom B., Booij, Leo H. D. J., Crul, Jan F.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1985

Language:

english

File:

PDF, 632 KB

english, 1985

17

Enterohepatic Cycling and Pharmacokinetics of Oestradiol in Postmenopausal Women

TOM B. VREE, CEES J. TIMMER

Journal:

Journal of Pharmacy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 698 KB

english, 1998

18

Gentamicin???PMMA Beads

WALENKAMP, GEERT H.I.M., VREE, TOM B., VAN RENS, THEO J.G.

Journal:

Clinical Orthopaedics and Related Research®

Year:

1986

Language:

english

File:

PDF, 782 KB

english, 1986

19

Acetylation and Hydroxylation of Sulphatroxazole by the Turtle Pseudemys Scripta Elegans

Dr. Tom B. Vree, Jeroen B. Vree, Yechiel A. Hekster, Jacques F. M. Nouws

Journal:

Transboundary and Emerging Diseases

Year:

1987

Language:

english

File:

PDF, 936 KB

english, 1987

20

Differences Between Lovastatin and Simvastatin Hydrolysis in Healthy Male and Female Volunteers: Gut Hydrolysis of Lovastatin is Twice that of Simvastatin

Vree, Tom B., Dammers, Erik, Ulc, Ivan, Horkovics-Kovats, Stefan, Ryska, Miroslav, Merkx, IJsbrand

Journal:

The Scientific World JOURNAL

Year:

2003

Language:

english

File:

PDF, 1.13 MB

english, 2003

21

Pharmacokinetic analysis and anticonvulsant activity of two polyesteric prodrugs of valproic acid

Salim Hadad, Tom B. Vree, Eppo Van Der Kleijn, Meir Bialer

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 464 KB

english, 1993

22

Pharmacokinetics of Anthracyclines in Dogs: Evidence for Structure-Related Body Distribution and Reduction to Their Hydroxy Metabolites

Marijn J. M. Oosterbaan, Rita J. M. Dirks, Tom B. Vree, Eppo van der Kleijn

Journal:

Pharmaceutical Research

Year:

1984

File:

PDF, 914 KB

1984

23

Placental transfer and renal clearance of sulphamethoxazole and its metabolite N4-acetylsulphamethoxazole in a pregnant ewe

TOM B. VREE, JOKE J. REEKERS-KETTING, JAC F. M. NOUWS, THEO H. M. ARTS

Journal:

Journal of Veterinary Pharmacology and Therapeutics

Year:

1983

Language:

english

File:

PDF, 299 KB

english, 1983

24

Ergot Alkaloids

Dr Akosua N. J. A. de Groot, Pieter W. J. van Dongen, Tom B. Vree, Yechiel A. Hekster, Jos van Roosmalen

Journal:

Year:

1998

Language:

english

File:

PDF, 311 KB

english, 1998

25

Oral administration of methylergometrine shows a late and unpredictable effect on the non-pregnant human menstruating uterus

Akosua N.J.A. de Groot, Pieter W.J. van Dongen, Tom B. Vree, Tom K.A.B. Eskes

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Year:

1995

Language:

english

File:

PDF, 645 KB

english, 1995

26

Pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl glucuronides in humans

Tom B. Vree, Magdalena Van Den Biggelaar-Martea, Corrien P. W. G. M. Verwey-Van Wissen, Jeroen B. Vree, Pieter J. M. Guelen

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 558 KB

english, 1993

27

Interaction between the renal excretion rates of β2-microglobulin and gentamicin in man: Potentials of β2-microglobulin excretion as an early prediction of gentamicin induced nephrotoxicity

Geert H.I.M. Walenkamp, Tom B. Vree, Pieter J.M. Guelen, Babs Jongman-Nix

Journal:

Clinica Chimica Acta

Year:

1983

Language:

english

File:

PDF, 337 KB

english, 1983

28

Pharmacokinetics and Anticonvulsant Activity of Three Monoesteric Prodrugs of Valproic Acid

Khalil Badir, Abdulla Haj-Yehia, Tom B. Vree, Eppo Kleijn, Meir Bialer

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 686 KB

1991

29

The effect of surgery on the renal excretion of β2-microglobulin

Geert H.I.M. Walenkamp, Tom B. Vree, Pieter J.M. Guelen, Babs Jongman-Nix

Journal:

Clinica Chimica Acta

Year:

1983

Language:

english

File:

PDF, 606 KB

english, 1983

30

N‐oxidation, N‐demethylation, and excretion of pefloxacin by the turtle Pseudemys scripta elegans

Vree, Tom B., Vree, Jeroen B., Baars, Ita M., Hekster, Yechiel A., Nouws, Jacques F. M.

Journal:

Veterinary Quarterly

Year:

1988

Language:

english

File:

PDF, 676 KB

english, 1988

31

Rapid quantitative determination of seven anthracyclines and their hydroxy metabolites in body fluids

Marijn J.M. Oosterbaan, Rita J.M. Dirks, Tom B. Vree, Eppo Van Der Kleijn

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1984

Language:

english

File:

PDF, 595 KB

english, 1984

32

Epidural Metabolism of Articaine to its Metabolite Articainic Acid in Five Patients after Epidural Administration of 600 mg Articaine

TOM B. VREE, GERTJAN E. C. J. M. VAN OSS, MATHIEU J. M. GIELEN, LEO H. D. J. BOOIJ

Journal:

Journal of Pharmacy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 492 KB

english, 1997

33

Clinical Pharmacokinetics of a Massive Overdose of Carbamazepine and Acute Renal Failure

Dr Tom B. Vree, Roelof van Dalen, Yvette Geerts, Eleonora W. J. van Ewijk-Beneken Kolmer

Journal:

Clinical Drug Investigation

Year:

1997

Language:

english

File:

PDF, 185 KB

english, 1997

34

Combination of methotrexate and sulphasalazine in patients with rheumatoid arthritis: pharmacokinetic analysis and relationship to clinical response

CEES J. HAAGSMA, FRANS G. M. RUSSEL, TOM B. VREE, PIET L. C. M. VAN RIEL, LEVINUS B. A. VAN DE PUTTE

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 276 KB

english, 1996

35

Clinical Consequences of the Biphasic Elimination Kinetics for the Diuretic Effect of Furosemide and its Acyl Glucuronide in Humans

TOM B. VREE, J. A. M. VAN DER VEN ANDRÉ

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

36

Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N 4 ‐acetylsulphamethoxazole in the turtle Pseudemys scripta elegans

Vree, Tom B., Vree, Jeroen B., Hekster, Yechiel A., Nouws, Jacques F. M.

Journal:

Veterinary Quarterly

Year:

1987

Language:

english

File:

PDF, 685 KB

english, 1987

37

Variable Plasma/Liver and Tissue Esterase Hydrolysis of Simvastatin in Healthy Volunteers after a Single Oral Dose

Dr Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Myroslav Ryska, Ijsbrand Merkx

Journal:

Clinical Drug Investigation

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

38

Saturable Active Tubular Reabsorption in the Renal Clearance of Mesalazine in Human Volunteers

Dr Tom B. Vree, Erik Dammers, Peter S. Exler, Fritz Sörgel, Robert A. A. Maes

Journal:

Clinical Drug Investigation

Year:

2000

Language:

english

File:

PDF, 199 KB

english, 2000

39

Analysis of N4-trideuteroacetylsulphamerazine and its metabolites sulphamerazine and N4-acetylsulphamerazine in man by means of high-performance liquid chromatography and mass spectrometry

Tom B. Vree, Marian W. Tijhuis, Margriet Baakman, Chiel A. Hekster

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1983

Language:

english

File:

PDF, 556 KB

english, 1983

40

Rapid simultaneous determination of baclofen and its γ-hydroxy metabolite in urine by high-performance liquid chromatography with ultraviolet detection

Eveline W. Wuis, Ludy E.C. Van Beijsterveldt, Rita J.M. Dirks, Tom B. Vree, Eppo Van Der Kleyn

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1987

Language:

english

File:

PDF, 319 KB

english, 1987

41

Explorative Pharmacokinetic Study of Preoperative Administration of Morphine 50mg Sustained-Release Capsules (Kapanol™ to Surgical Patients

Leo H. D. J. Booij, Dr Tom B. Vree, Heleen Koppers-Hoyset, Aart J. Lagerwerf

Journal:

Clinical Drug Investigation

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

42

Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N 4 ‐cacetylsulphamethoxazole in the snail Cepaea hortensis

Vree, Tom B., Vree, Monika L., Nouws, Jacques F. M.

Journal:

Veterinary Quarterly

Year:

1987

Language:

english

File:

PDF, 701 KB

english, 1987

43

Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: allergic or toxic?

Koopmans, Peter P., van der Ven, André J.A.M., Vree, Tom B., van der Meer, Jos W.M.

Journal:

Year:

1995

File:

PDF, 4.73 MB

1995

44

Pharmacokinetics of Sulfamethoxazole with its Hydroxy Metabolites and N4-Acetyl-, N1-Glucuronide Conjugates in Healthy Human Volunteers

Dr Tom B. Vree,André J. A. M. van der Ven…

Journal:

Clinical Drug Investigation

Year:

1995

Language:

english

File:

PDF, 794 KB

english, 1995

45

Comment: potential theophylline toxicity with enoxacin

Wijnands, Giel J.A., Vree, Tom B., Van Herwaarden, Cees L.A.

Journal:

Drug Intelligence & Clinical Pharmacy

Year:

1987

Language:

english

File:

PDF, 157 KB

english, 1987

46

Bioavailabilities of Quercetin-3-Glucoside and Quercetin-4′-Glucoside Do Not Differ in Humans

Olthof, Margreet R., Hollman, Peter C. H., Vree, Tom B., Katan, Martijn B.

Journal:

Journal of Nutrition

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

47

High-performance Liquid-chromatographic-Atmospheric-pressure Chemical-ionization Ion-trap Mass-spectrometric Identification of Isomeric C6-hydroxy and C20-hydroxy Metabolites of Methylprednisolone in the Urine of Patients Receiving High-dose Pulse Therapy

TOM B. VREE, LOUIS MALJERS, NOUD VAN DEN BORG, NICO M. M. NIBBERING, CORRIEN P. W. G. M. VERWEY-VAN WISSEN, AART J. LAGERWERF, ROBERT A. A. MAES, P. JOZEF H. JONGEN

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 137 KB

english, 1999

48

Bioavailability and Pharmacokinetics of Sublingual Oxytocin in Male Volunteers

Groot, Akosua N. J. A., Vree, Tom B., Hekster, Yechiel A., Pesman, Gerard J., Sweep, Fred C. G. J., Dongen, Pieter J. W., Roosmalen, Jos

Journal:

Journal of Pharmacy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 438 KB

english, 1995

49

Acetylation and deacetylation of sulphonamides in dogs

TOM B. VREE, JOKE J. REEKERS-KETTING, CHIEL A. HEKSTER, JAC F. M. NOUWS

Journal:

Journal of Veterinary Pharmacology and Therapeutics

Year:

1983

Language:

english

File:

PDF, 174 KB

english, 1983

50

Plasma and bone concentrations of cefuroxime and flucloxacillin: Oral versus parenteral administration in 20 arthroplasties

Ferrero, Miguel M Alvarez, Vree, Tom B, Baars, Arita M, Slooff, Tom J J H

Journal:

Acta Orthopaedica

Year:

1993

Language:

english

File:

PDF, 404 KB

english, 1993

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